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What Is ENBREL?

ENBREL is a prescription medicine that can be self-injected. It is used to treat five long-term inflammatory diseases: moderate to severe rheumatoid arthritis (RA), moderate to severe plaque psoriasis, psoriatic arthritis, moderate to severe juvenile idiopathic arthritis (JIA), and ankylosing spondylitis (AS).

ENBREL is grouped within a class of medications called biologic response modifiers, or biologics. By working on the immune system, biologics block proteins that contribute to the disease process. Because ENBREL suppresses the immune system, patients are at a greater risk for getting serious infections.

The science behind ENBREL

Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis have too much TNF in their bodies. ENBREL reduces levels of the active form of TNF.

The clinical history of ENBREL

• ENBREL was the first biologic approved for moderate to severe rheumatoid arthritis
• ENBREL has an established safety profile
• ENBREL has over 10 years of continuous safety data in patients with rheumatoid arthritis

Talk with Your Doctor How ENBREL Works

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The product information provided in this site is intended only for residents of the United States.
The products discussed herein may have different product labeling in different countries.
Manufactured by Immunex Corporation, Thousand Oaks, CA 91320. Marketed by Amgen Inc. and Pfizer Inc.
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