Injection Options and Demos
ENBREL is injected just under the skin with a needle in a part of the body that is easy to reach. ENBREL should be injected in the front of the middle thighs, the stomach (avoiding the 2-inch area around the belly button), or the outer area of the upper arms. With the design of the Enbrel® (etanercept) SureClick® autoinjector, you'll never even have to see the needle.
Before starting ENBREL, tell your doctor if you think you have an infection, or if you have a fever, cough, flu-like symptoms, or an open sore. Do not start ENBREL if you have any kind of infection. While taking ENBREL, call your doctor immediately if you have an infection as ENBREL can increase your risk of infection.
Multiple injection options
ENBREL offers the convenience and flexibility of multiple administration options.
Choose the method you are most comfortable with or one that is recommended by your doctor:
- Enbrel® SureClick® 50-mg/mL autoinjector
- ENBREL single-use prefilled syringe
- ENBREL 25-mg multi-use vial free-hand method
- ENBREL 25-mg vial adapter method
Step-by-step injection demos
You or a caregiver should receive training from your health care professional
for the first injection of ENBREL in the doctor's office. After the training,
you can self-inject ENBREL in the comfort of your home. Click below to view
step-by-step instructions.
Injection site reactions such as redness, rash, swelling, itching, or bruising
may occur. These symptoms usually go away within 3 to 5 days. If you experience
these reactions and they don't go away or get worse, call your doctor.
Patients can inject ENBREL using a 50 mg/mL prefilled autoinjector.
Enbrel® SureClick®
50-mg/mL autoinjector
Patients can inject ENBREL using a 50-mg/mL prefilled autoinjector. The Enbrel® SureClick® autoinjector is for single use only.
Chapter 1: Preparation
Chapter 2: Prepping the Injection Site
Chapter 3: Injection Steps
Chapter 4: Disposal
Patients can inject ENBREL using a 50 mg/mL and 25 mg/mL prefilled syringe.
ENBREL single-use prefilled syringe
Patients can inject ENBREL using a prefilled syringe available in 50-mg/mL and 25-mg/0.5mL dosage strengths. The prefilled syringe is for single use only.
Chapter 1: Preparation
Chapter 2: Set Up
Chapter 3: Prepping the Injection Site
Chapter 4: Checking the Needle
Chapter 5: Injecting ENBREL
Chapter 6: Disposal
For children with juvenile idiopathic arthritis (JIA), caregivers can use the multi-use vial free-hand method.
ENBREL 25-mg multi-use vial free-hand method
For some children with juvenile idiopathic arthritis (JIA), one vial of ENBREL solution can be used for more than one dose. The free-hand method should be used for these children.
Step 1: Setting Up
Step 2: Preparing the ENBREL Solution
Step 3: Withdrawing the Solution
Step 4: Preparing for Injection
Step 5: Injecting ENBREL
Step 6: Disposal
People who use a single vial of ENBEL for each dose may use the vial adapter device to assist with mixing and withdrawing ENBREL.
ENBREL 25-mg vial adapter method
People who use a single vial of ENBREL for each dose may use the vial adapter device to assist with mixing and withdrawing ENBREL.
Step 1: Setting Up
Step 2: Preparing the ENBREL Solution
Step 3: Withdrawing the Solution
Step 4: Preparing for Injection
Step 5: Injecting ENBREL
Step 6: Disposal
Please see Patient Instructions for Use.
Please see Full Prescribing Information, Important Safety Information, and Medication Guide for complete details about ENBREL.
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